Rofecoxib

A chemical substance C17H14O4S molecular weight 31436 used in medicine as an analgesic to alleviate pain and inflammation it is a synthetic compound and is marketed by Merck amp Co under the trade name Vioxx in tablets giving dosages of 125 or 25 milligrams It is classed as a non steroidal anti inflammatory drug NSAID Chemically it is 4 4 methylsulfonyphenyl 3 phenyl 25H furanone Its chemical structure contains two phenyl rings and a furanone ring It is believed to act by inhibition of prostaglandin biosynthesis through inhibition of the enzyme cyclooxygenase 2 COX 2 unlike aspirin it does not inhibit cyclooxygenase 1